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Grants to USA Scientists Affiliated with Eligible Institutions for Innovative Scientific Research

NIH Director's Transformative Research Award


Agency
Federal

GrantWatch ID#
157816

Funding Source
U.S. Department of Health and Human Services (HHS) - National Institutes of Health (NIH)
CFDA Number: 93.310
Funding or PIN Number: RFA-RM-23-006
Array ( [0] => American Samoa (USA); [1] => Guam (USA); [2] => Puerto Rico (USA); [3] => Virgin Islands (USA); [4] => Northern Mariana Islands (USA); )

Geographic Focus
All USA
USA Territories: American Samoa (USA);   Guam (USA);   Puerto Rico (USA);   Virgin Islands (USA);   Northern Mariana Islands (USA);

Important Dates
Deadline: 09/01/23 5:00 PM Local Time Save

Grant Description
Grants to USA and territories scientists and groups of scientists affiliated with IHEs, nonprofit and for-profit organizations, and government agencies for innovative and unconventional scientific research. Applicants are advised that required registrations may take several weeks to complete. Funding is intended to support original research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies.

The NIH Directors Transformative Research Award Program supports individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. For the program to support the best possible researchers and research, applications are sought which reflect the full diversity of the nations research workforce. Individuals from diverse backgrounds, including those from underrepresented groups (see, Notice of NIH's Interest in Diversity, NOT-OD-20-031) are strongly encouraged to apply to this Funding Opportunity Announcement. In addition, applications are welcome from the full spectrum of eligible institutions in all geographic locations and in all topic areas relevant to the broad mission of NIH, including, but not limited to,  behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of relevance to the NIH. The NIH Directors Transformative Research Award is a component of the High-Risk, High-Reward Research program of the NIH Common Fund.

Several key features of this FOA are designed to emphasize to applicants and peer reviewers that Transformative Research applications are very different from conventional, investigator-initiated research applications. The Transformative Research application focuses on the importance of the problem, the novelty of the hypothesis and/or the proposed methodology, and the magnitude of the potential impact rather than on preliminary data or experimental details. Reviewers will be instructed to emphasize the significance and innovation of the application in their evaluations. Applicants and reviewers should keep the goal of the Transformative Research Award initiative in mind throughout the process– to solicit and fund unusually innovative and potentially transformative research.



Recipient

Eligibility
  • City or township governments
  • County governments
  • For profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Others (see text field entitled "Additional Eligibility Criteria" for clarification)
  • Small businesses
  • Special district governments
  • State governments

Additional Eligibility Criteria
Higher Education Institutions
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education
The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)

Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)

For-Profit Organizations
- Small Businesses
- For-Profit Organizations (Other than Small Businesses)

Local Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)

Federal Government
- Eligible Agencies of the Federal Government, which excludes NIH Intramural investigators
- U.S. Territory or Possession

Other
- Independent School Districts
- Public Housing Authorities/Indian Housing Authorities
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations

Eligible Individuals (Program Director/Principal Investigator): Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with their organization to develop an application for support. Individuals from diverse backgrounds, including underrepresented racial and ethnic groups, individuals with disabilities, and women are always encouraged to apply for NIH support.

Ineligible
Foreign Institutions:
- Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
- Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Pre-Proposal Conference
NIH Director's Transformative Research Award Q&A Webinar

Prospective applicants are invited to a pre-application webinar on June 27, 2023, from 2:00-3:30 PM ET.

NIH program and review staff will discuss funding opportunity RFA-RM-23-006 and answer questions about the application and review process during this pre-application interactive Q&A webinar.

Questions for the webinar should be submitted ahead of time via email by 11:59 PM local time on June 23, 2023. Additional questions may be taken during the webinar if time allows. Register for the webinar and join on Webex. The webinar will be recorded and posted on the Transformative Research Award website.

More information and to register:
https://nih.webex.com/webappng/sites/nih/meeting/register/0bc998a8bbbf43ff9a5af2abb167b7fc?ticket=4832534b00000006c826d56a79bff2ae374c4800f32732f3c4e03d56a4aa1ceabe11155b82820e0b×tamp=1684914112975&RGID=r268a67c90db0e2aa52d5aabb8a3d4a56

Pre-Application Information
Timelnie:
- Open Date (Earliest Submission Date): August 01, 2023
- Applications are due: September 1, 2023
- Scientific Merit Review: March 2024
- Advisory Council Review: May 2024
- Earliest Start Date: August 2024

All applications are due by 5:00 PM local time of applicant organization.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

No late applications will be accepted for this Funding Opportunity Announcement.

There are several options available to submit your application through Grants.gov to NIH and Department of Health and Human Services partners. You must use one of these submission options to access the application forms for this opportunity.
1. Use the NIH ASSIST system to prepare, submit and track your application online.
2. Use an institutional system-to-system (S2S) solution to prepare and submit your application to Grants.gov and eRA Commons to track your application. Check with your institutional officials regarding availability.
3. Use Grants.gov Workspace to prepare and submit your application and eRA Commons to track your application.

Applicant organizations must complete and maintain the following registrations:
- System for Award Management (SAM)– Applicants must complete and maintain an active registration, which requires renewal at least annually. The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code. NATO Commercial and Government Entity (NCAGE) Code – Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM. Unique Entity Identifier (UEI)- A UEI is issued as part of the SAM.gov registration process. The same UEI must be used for all registrations, as well as on the grant application.
- eRA Commons - Once the unique organization identifier is established, organizations can register with eRA Commons in tandem with completing their Grants.gov registration; all registrations must be in place by time of submission. eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application.
- Grants.gov – Applicants must have an active SAM registration in order to complete the Grants.gov registration.

Cost Sharing or Matching Requirement: No

RFA:
https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-23-006.html

View this opportunity on Grants.gov:
https://www.grants.gov/web/grants/view-opportunity.html?oppId=347164

Additional Funding Information

Estimated Total Program Funding:

$8,000,000

Number of Grants
7

Term of Contract
The maximum project period is five years.

Contact Information
Apply Online Using ASSIST:
https://public.era.nih.gov/assist/public/login.era?TARGET=https%3A%2F%2Fpublic.era.nih.gov%3A443%2Fassist%2F

Questions for the webinar should be submitted ahead of time to Transformative_Awards@mail.nih.gov.

General Grants Information (Questions regarding application instructions, application processes, and NIH grant resources)
Email: GrantsInfo@nih.gov (preferred method of contact)
Telephone: 301-637-3015

Grants.gov Customer Support (Questions regarding Grants.gov registration and Workspace)
Contact Center Telephone: 800-518-4726
Email: support@grants.gov

Scientific/Research Contact(s)
Patricia Labosky, Ph.D.
Office of the Director (OD)
Email: Transformative_Awards@mail.nih.gov

Peer Review Contact(s)
Center for Scientific Review (CSR)
Email: FOAReviewContact@csr.nih.gov

Financial/Grants Management Contact(s)
Michael Morse
Office of the Director (OD)
Telephone: 301-435-5446
Email: morsem@od.nih.gov

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